Coronary artery disease (CAD) remains the leading cause of death in the United States, responsible for roughly 600,000 deaths every year. While traditional risk factors like smoking, high cholesterol, and diabetes are well-known, emerging research highlights another, less obvious contributor: oral infections.

A landmark study from the University of Helsinki found that hidden tooth infections, particularly apical periodontitis (an infection at the root tip of a tooth), are associated with a 2.7x higher risk of acute coronary events. This is true even in patients without symptoms . These infections often go unnoticed without dental X-rays, making regular checkups critical.
The link appears to begin early in life. A 2019 Finnish study tracking individuals from childhood found that children with signs of oral infections had nearly double the risk of developing early atherosclerosis as adults.
How Oral Infections Can Affect the Heart
Chronic oral infections contribute to systemic inflammation, which plays a key role in the development of atherosclerosis. Atherosclerosis is the narrowing and hardening of arteries due to plaque buildup. Some oral bacteria have even been found in arterial plaques, suggesting they may migrate through the bloodstream and contribute directly to cardiovascular disease .
Research also shows that gum disease, tooth decay, and tooth loss associate with higher rates of coronary artery disease. Meta-analyses suggest a 30%–60% increased risk among individuals with untreated periodontal conditions.
Treatment and Prevention Options
The good news is that treating oral infections may help reduce cardiovascular risks. One study found that individuals with at least one root-filled tooth (i.e., one treated with a root canal) had significantly lower rates of coronary artery disease and cardiovascular mortality.

Root canal therapy involves removing infected tissue from inside the tooth, thoroughly cleaning the canal, and sealing it. Then, a dentist places a dental crown on the tooth to restore its strength, function, and appearance. At Contemporary Cosmetic Dentistry in Austin, we offer custom porcelain crowns designed to blend seamlessly into your smile.
Regular dental exams are your best defense. Many infections are asymptomatic in their early stages and can only be identified through professional evaluation. Dr. John Schmid uses advanced diagnostic tools, including digital X-rays, to detect issues early and recommend treatment before infections can affect your overall health.
Protect Your Smile and Your Heart
Maintaining a healthy mouth isn’t just about avoiding cavities; it could help protect your heart. If you have concerns about tooth pain, swelling, or a history of dental problems, don’t wait for symptoms to worsen. Contact Contemporary Cosmetic Dentistry today to schedule an appointment at our Austin, Texas office. We’re here to help you stay healthy, starting with your smile.
Editor’s Note: This article was originally published in August 2016 and was updated on August 22, 2025.
